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Fertility Plus Research


IVF-LUBE Study - lipiodol uterine bathing effect for enhancing the results of in vitro fertilisation, a multicentre randomised trial, for those with Endometriosis or Recurrent Implantation Failure 

This trial will examine the effectiveness of a procedure in improving the chance of success in women scheduled to undergo in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) fertility treatment, in those with Endometriosis and/or Recurrent Implantation Failure (Three consecutive good quality embryo replacements, fresh or thawed, from an IVF cycle, that have failed to implant)


There is evidence to confirm the effectiveness of lipiodol in improving the chance of couples becoming pregnant naturally, where infertility is unexplained and particularly where the woman has endometriosis. This research study aims to assess whether lipiodol also has an effect in improving the chance of a successful IVF or ICSI treatment.

To be eligible you need to fulfil the following Inclusion Criteria:

-Have a diagnosis of Endometriosis or Recurrent Implantation Failure
-Be about to undergo a cycle of IVF or ICSI in the near future (within the next 6 months)
-Age 39 years or younger
-Infertility of more than 1 year
-Both Tubes Patent ie/not blocked
-No iodine allergy

-Not having an egg donor IVF or ICSI cycle

Enquiries regarding this study should be directed to Dr Shelley Reilly, Fellow in Reproductive Endocrinology and Infertility, and the principal Investigator responsible for this study.


Mobile: 021 915 771

National Women's Health
Phone: 09 307 4949
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